County history
Anderson County Was Named for the Last Vice President of the Republic of Texas
Anderson County was created in 1846 from Houston County. It was named after Kenneth Lewis Anderson, the last vice president of the Republic of Texas, who died in office in 1845.
The Texas Legislature created Anderson County on March 24, 1846. It was carved out of Houston County. Lawmakers named it after Kenneth Lewis Anderson (1805–1845). Anderson was the last vice president of the Republic of Texas, serving under President Anson Jones. He ran the Texas Senate session in June 1845 when Congress voted to approve annexation by the United States.
Anderson never made it home from that session. He fell ill on the way back and died on July 3, 1845, at the Fanthorp Inn — a stagecoach stop in what is now Grimes County. He was 39 years old. Many thought he would become the first governor of the new state of Texas. His law partner, J. Pinckney Henderson, won that office instead.
Palestine became the county seat. It was named after Palestine, Illinois, the former home of early settler Daniel Parker. By 1850, the county's population was 2,884. The Texas State Historical Association's Handbook of Texas covers this full history.
Source to confirm: TSHA Handbook of Texas — Anderson County