Major Roads
Two Major Interstates Cross the County
I-10 and I-35 both run through Guadalupe County, making it a crossroads between San Antonio, Austin, and Houston.
I-10 crosses the county east of San Antonio, passing through Seguin and connecting to Houston. TxDOT has an active widening project on I-10 between FM 464 and SH 130 in the county. Expect construction delays if you drive that stretch.
I-35 runs along the county's western edge near Schertz. It connects San Antonio to Austin. A large I-35 expansion project called NEX covers roughly 20 miles through Bexar, Comal, and Guadalupe counties. Both projects can affect your daily commute. Check txdot.gov for current project timelines before you drive.
Source to confirm: TxDOT – I-10 Guadalupe Widening Project